Klopp revealed afterwards that the 25-year-old had been taken to hospital for medical tests, with Liverpool and Egypt now waiting anxiously to discover the full severity of a shoulder problem.
Such a strike deserved to be the victor, although it was his long-range shot that beat the embarrassed Karius in the 83rd minute that made sure of the victory. He is the quiet Galactico and, in fact, was conspicuous by his absence during Real's media day ahead of this final when the focus was inevitably on Ronaldo and his match-up with Mohamed Salah.
At the very highest level, the best players perform.
Liverpool fans will point to three things that cost their club the Champions League final-superstar striker Mohamed Salah's shoulder injury and two awful mistakes by goalkeeper Loris Karius. "I've never scored bicycle-kick before, I've had many attempts, so it was nice to see one go in on such an important occasion". Liverpool players were inconsolable at full time, needless to say, but once the pain of defeat subsides they can look back with huge pride at their achievements in the competition this term.
Salah has had an incredible season, scoring 44 for Liverpool in all competitions.
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Salah's exit gave Real an immediate lift because they had been nervous and edgy up until that point in the game.
"Yes, it is", Klopp confirmed to BT Sport.
At that stage the suspicion was that Liverpool were mentally gone, but four minutes later a right-wing corner brought an equaliser, Virgil van Dijk heading down for Mane to stab in.
Had Salah been fit to stay on the pitch, it could have been a different story.
Zidane stood and applauded and he was joined by thousands of Liverpool fans filling nearly three-quarters of the ground who, despite the cruel blow, appreciated the quality.