In 2012, it was reported a 40-year-old in the United Kingdom literally coughed out her lung through her ribs.
Wieselthaler told the Atlantic that in this case, the patient had an infection that increased levels of a protein called fibrinogen, which helps blood clots form; and higher levels of fibrinogen could have helped the man's large clot to stay intact when it was coughed up.
The man reportedly had a medical history that included heart failure; he had previously been fitted for a pacemaker.
The unidentified patient was receiving treatment in the Intensive Care Unit at the University of California San Francisco Medical Center, according to a November 29 article in the New England Journal of Medicine.
Doctors were surprised by the blood clot cast.
Doctors placed a ventricular assist device, a heart pump, into him to treat his condition, but he showed signs of respiratory distress.
But one man in California shocked his doctors when he coughed up an unusual-looking blood clot: It was in the shape of his lung.
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More specifically it's a six-inch-wide, unbroken cast of the right bronchial tree, part of the tubular network that distributes air to the lungs.
According to doctors, the clot was a near flawless cast of the man's right bronchial tree.
"We were astonished", Dr Wieselthaler said. One week after extubation, he died from complications of heart failure (volume overload and poor cardiac output) despite placement of the ventricular assist device.
The 25-year-old mum went on to recover fully and delivered a healthy, full-term baby soon after.
"It's a curiosity you can't imagine".