Alfonso Cuaron accepts the award for best director for "Roma" at the 24th Critics Choice Awards in Santa Monica, California.
Elsie Fisher won the best new actress honor for her breakthrough role in "Eighth Grade".
Critics' Choice Awards are bestowed annually by the Broadcast Film Critics Association [BFCA] and Broadcast Television Journalists Association [BTJA] to honor the finest in cinematic and television achievement.
She then thanked "magical filmmaker and human" Bradley Cooper, and said she would always "cherish" the experience of working with him.
Mahershala Ali ("Green Book") walked away with a Best Supporting Actor win, while Regina King ("If Beale Street Could Talk") won for Best Supporting Actress.
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When the award was presented, Amy Adams was the first to be announced as a victor. When she was in pain, so was I. "Maisel" won the top comedy honor for the second year in a row, and series star Rachel Brosnahan also was a repeat victor for best actress in a comedy series.
Tom Cruise vehicle "Mission: Impossible - Fallout" won the Best Action Movie award, beating Marvel-Disney box office blockbusters "Black Panther" and "Avengers: Infinity Wars".
The Favourite, which had led the way with 14 nominations, won the best acting ensemble prize, while Crazy Rich Asians won best comedy.
Newton won best supporting actress in a drama series for her role in Westworld, while Rhys took home the male equivalent for The Americans.
Roma also had a great night at the Golden Globes, winning two out of the three awards it was up for.