"I can't tell you how frustrating that is", Clooney said.
The Gravity star went on to directly reference the alleged handwritten letter, in which Meghan reportedly accused her dad Thomas of having "broken my heart into a million pieces" by telling falsehoods to the media. Clooney, a friend of the duchess, complained that she was "being pursued and vilified and chased in the..."
"We've seen how that ends", Clooney continued.
Former Suits actress Meghan, 37, is estranged from her father following a string of high-profile incidents since she became engaged to Harry.
Usher & Rich the Kid Attacked at Recording Studio, Shots Fired
Eye witnesses say the man who opened fire was running away from the studio when he started shooting behind him. The suspects were reported to be seen fleeing the scene with a lot of cash and jewellery while firing shots.
In a previous interview with Harper's Bazaar in 2007, the duchess said that she and Diana (who was her fourth cousin) were much more like siblings than rivals.
He has repeatedly complained that his relationship with his daughter has broken down and made numerous public appeals for her to get in touch with him, including an appearance on Good Morning Britain. While we don't know the gender or possible names, it's clear that Charles will have a special bond with his fourth grandchild.
They mentioned a five-page letter she wrote to her father, Thomas Markle Sr.
Meghan, who was wearing a white Calvin Klein dress and a white Amanda Wakeley coat, held hands with Harry as she entered the museum where she was greeted with flowers given by 12-year-old Sage Saunders.
Over the weekend, a deeply personal letter allegedly written by the duchess to her father in August, was published - months after he missed her wedding.
During Harry and Meghan's tour of Australia, New Zealand, Fiji and Tonga, last fall, they unveiled six dedications to the QCC and welcomed commitment to the initiative by its latest member, Kiribati. "She can write all the fake, contrived letters she wants to show off her penmanship but that's all it is".