Both men then proceeded to throw punches at one another before Ibaka walked away.
Cleveland was winning 91-77 at the time of the incident and went on to win 126-101. Cleveland was ahead for most of the half and outscored Toronto 32-22 in the third quarter.
With 1.0 second remaining in the third quarter, the Raptors' Serge Ibaka and the Cavaliers' Marquese Chriss were both going after the ball following a full-court pass in hopes of beating the buzzer to end the quarter.
Chriss and Ibaka both threw punches at each other, luckily with neither landing solidly, and they were separated quickly and ushered to their respective benches. The Cavaliers build the lead to 27 points late in the game.
Chiefs Kingdom responds very favorably to Tyrann Mathieu signing
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On the heels of a game in which they knocked down a franchise-record-tying 21 3-pointers, the Raptors shot a subpar 11-for-39 (28.2 percent) from deep against the Cavs. Neither player were available for comment afterwards. Ibaka fell to the floor and Chriss must have said something that Ibaka didn't take kindly.
The Raptors are vying for an Eastern Conference win this season, as their team is second in the East now, with a 48-20 record. He is averaging 15.2 points and 8.1 rebounds per game this season.
First-year head coach Nick Nurse has led his team to a 47-19 record so far this season.
Raptors: G Fred Van Vleet (ligament tear in left thumb) missed his 11th straight game. Jordan Clarkson led the Cavaliers with 20 points in the loss. Toronto tied a team record with 21 made 3-pointers against the Heat on Sunday. The Washington product has averaged 7.9 points per game in three National Basketball Association seasons. G Patrick McCaw made his first start with the team Sunday at Miami with Leonard sidelined, scoring 10 points in 26 minutes.